Comprehensive Preclinical & Toxicological Testing
- Acute toxicity studies (oral, dermal, inhalation, parenteral)
- Skin irritation studies
- Eye irritation studies (OECD guidelines)
- Repeated dose toxicity studies (sub-acute, sub-chronic, chronic)
- Reproductive and developmental toxicity (DART)
- Maximum tolerated dose (MTD) studies
- Dose range finding (DRF) studies
- In-vitro toxicology studies (AMES, enhanced AMES)
- Ecotoxicology studies
- Pharmacokinetic and toxicokinetic studies
- Dermal sensitization studies
- Efficacy study models (anti-cancer, anti-diabetes, xenograft, psoriasis)
- Preclinical ENMACHIP studies
- In-silico safety studies (ICH M7)
- Carcinogenicity studies
- Neurotoxicity studies
- Toxicological risk assessment (TRA)
- Skin sensitization studies (GPMT/Buehler)
- DMPK studies
- PDE studies (EMA/CHMP/CVMP/SWP/169430/2012)
What types of toxicological studies do you offer?
We provide acute, repeated dose, reproductive, genotoxicity, carcinogenicity, and neurotoxicity studies.
Do you support regulatory toxicology requirements?
Yes, our studies are aligned with global regulatory guidelines including OECD, ICH, and EMA standards.
What is DART testing?
DART (Developmental and Reproductive Toxicity) evaluates potential effects on reproduction and fetal development.
Do you offer in-vitro and in-silico toxicology studies?
Yes, we provide AMES, enhanced AMES, and in-silico safety studies as per ICH M7 guidelines.
Can you support pharmacokinetic and DMPK studies?
Yes, we conduct pharmacokinetic, toxicokinetic, and DMPK studies for comprehensive safety evaluation.
Safety Evaluated. Confident Outcomes.
Preclinical and toxicological studies are essential to evaluate the safety, efficacy, and risk profile of pharmaceutical, biotechnology, and chemical products. At Accuprec, we offer a comprehensive range of toxicological services designed to support early-stage research, regulatory submissions, and product development.
Our capabilities include acute and repeated dose toxicity studies, reproductive and developmental toxicity (DART), genotoxicity, carcinogenicity, and toxicokinetic assessments. We also provide advanced studies such as in-vitro toxicology, in-silico safety assessments, and toxicological risk evaluation aligned with global regulatory expectations.
With a strong scientific approach and regulatory expertise, we deliver reliable, reproducible, and audit-ready data to support informed decision-making and compliance.
Our Approach to Accurate & Compliant Testing
Requirement Understanding
We begin by understanding your product, testing requirements, and regulatory objectives to define a clear analytical strategy.
Method Development & Planning
Our team develops and optimizes analytical methods, ensuring alignment with ICH, USP, and global regulatory standards.
Testing & Analysis
Samples are tested using advanced instrumentation such as LC-MS/MS, ICP-MS, and other validated techniques for accurate results.
Reporting & Compliance Support
We deliver detailed, audit-ready reports and provide support for regulatory submissions and compliance requirements.
